Searchable abstracts of presentations at key conferences in endocrinology

ea0029p250 | Calcium & Vitamin D metabolism | ICEECE2012

Quantification of serum 25-hydroxyvitamin D: a comparison among immunoassay, HPLC-UV, and HPLC-MS

Saba A. , Bozic R. , Viccica G. , Maccheroni M. , Cianferotti L. , Chiellini G. , Raffaelli A. , Zucchi R. , Marcocci C.

Vitamin D deficiency is widespread among all age and ethnic groups. Serum 25-hydroxyvitamin D [25(OH)D] is the most reliable marker of vitamin D status. Adequate levels of serum 25(OH)D are necessary to sustain the pleiotropic effects of vitamin D, either skeletal (classical) or extra-skeletal (non-classical). Concentration levels ≧50 nmol/L (20 ng/ml) are required for optimal musculoskeletal health. However, levels above 75 nmol/L (30 ng/ml) may be necessary to maximiz...